August 26th 2001 was the first time I think that "Ohio" was played live - it's all fairly literal but that line, I think. Here's from my review at the time, on the actwin thing:
QUOTE
Then Linford and Karin stand, Linford leaves, and Karin mans the piano.Says "with a man like Linford around, who needs to play piano" but that she
still likes to write on it. She talks about growing up in E Central OH,
about 20mi from where Linford grew up and how mining-focused the whole area
is. She says how other couples grow up looking at the same moon or
something all the time, she and Linford were looking at the same strip mine
machines. She continued talking about growing up in that environment, going
out with friends, etc. Also about losing a neighbor boy or something to
drowning in a strip pit. Anyway, this all leads to "Hello Ohio". It pretty
much was a song about the things she just talked about, and the chorus if
you'd read it on paper or here would read a little dopey maybe ("I know
Ohio/like the back of my hand" was the second line of the refrain) but under
her great playing and emotive voice, was a really special song. The bridge
had a lot of names of friends (Holly/Mary/Natalie maybe) and that and the
whole of the song conjured a lot of beautiful images. The last line of the
chorus was something along the lines of "it's hard to see, the story end".
At the time this was going on, Karin's mother had just become sick. Just prior to that, K+L were contemplating a move from Ohio to elsewhere (maybe NYC) - so I'd bet a fair amount that that is fairly literal too.